The network response to Egf is tissue-specific

The network response to Egf is tissue-specific

Summary: Epidermal growth factor receptor (Egfr)-driven signaling regulates fundamental homeostatic processes. Dysregulated signaling via Egfr is implicated in numerous disease pathologies and distinct Egfr-associated disease etiologies are known to be tissue-specific. The molecular basis of this ti...

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Bibliographic Details
Main Authors: Beatrice W. Awasthi, João A. Paulo, Deborah L. Burkhart, Ian R. Smith, Ryan L. Collins, J. Wade Harper, Steven P. Gygi, Kevin M. Haigis
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:iScience
Subjects:
molecular biology
bioengineering
systems biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225004067
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http://www.sciencedirect.com/science/article/pii/S2589004225004067

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