Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

Service members and law enforcement personnel are frequently exposed to blast overpressure during training and combat due to the use of heavy weaponry such as large-caliber rifles, explosives, and ordnance. The cumulative effects of these repeated low-level (<4 psi) blast exposures can lead t...

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Bibliographic Details
Main Authors: Eyal Bar-Kochba, Catherine M. Carneal, Vanessa D. Alphonse, Andrea C. Timm, Amanda W. Ernlund, Carissa L. Rodriguez, Itzy E. Morales Pantoja, Lena Smirnova, Thomas Hartung, Andrew C. Merkle
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
traumatic brain injury
brain organoids
repeated blast
low-level blast
primary blast
in vitro model
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1553609/full
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https://www.frontiersin.org/articles/10.3389/fbioe.2025.1553609/full

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