Bimetallic Ca/Zn Nanoagonist Remould the Immunosuppressive Hepatocellular Carcinoma Microenvironment Following Incomplete Microwave Ablation via Pyroptosis and the STING Signaling Pathway

Bimetallic Ca/Zn Nanoagonist Remould the Immunosuppressive Hepatocellular Carcinoma Microenvironment Following Incomplete Microwave Ablation via Pyroptosis and the STING Signaling Pathway

Abstract During the treatment of solid tumors, local therapeutic approaches carry the risk of incomplete radical cure, which may lead to rapid tumor growth. Incomplete microwave ablation (iMWA) can induce tumors to exhibit highly invasive and uncontrollable growth, which is related to the immunosupp...

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Main Authors: Yuan Ling, Xiayi Liang, Kangning Yan, Guichun Zeng, Xiaoqi Zhu, Jinghang Jiang, Shaolong Lu, Xiaobo Wang, Yuying Zhou, Zhaoshen Li, Wei Mai, Duo Wang, Jie Chen
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
cellular pyroptosis
hepatocellular carcinoma
incomplete microwave ablation
JAK2‐STAT3 signaling pathway
STING pathway
Online Access:https://doi.org/10.1002/advs.202500670
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https://doi.org/10.1002/advs.202500670

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