High-Yield and Quantitative Purification Method for HIV Which Minimizes Forces Applied to Virions Utilized to Investigate Maturation of HIV-1 via Cryo-Electron Tomography

High-Yield and Quantitative Purification Method for HIV Which Minimizes Forces Applied to Virions Utilized to Investigate Maturation of HIV-1 via Cryo-Electron Tomography

HIV is a lentivirus characterized by its cone shaped mature core. Visualization and structural examination of HIV requires the purification of virions to high concentrations. The yield and integrity of these virions are crucial for ensuring a uniform representation of all viral particles in subseque...

Full description

Saved in:
Bibliographic Details
Main Authors: Benjamin Preece, Wiley Peppel, Rodrigo Gallegos, Gillian Ysassi, Gabriel Clinger, Nicole Bohn, Broti Adhikary, Luiza Mendonça, David Belnap, Michael Vershinin, Saveez Saffarian
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Viruses
Subjects:
HIV
infectivity
Gag-Pol
gRNA
Online Access:https://www.mdpi.com/1999-4915/17/3/364
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1999-4915/17/3/364

Similar Items