A humanized anti-Toll like receptor 4 antibody Fab fragment inhibits pro-inflammatory responses induced by lipopolysaccharide through TLR4 in vitro and in vivo
Introduction: Toll like receptor 4 (TLR4) and its co-receptor MD-2 recognize bacterial lipopolysaccharide (LPS), initiating responses to infections caused by Gram-negative bacteria. TLR4 also plays a role in various pathological processes, including viral infections and sterile inflammation. Howeve...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2025-06-01
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| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://www.jidc.org/index.php/journal/article/view/20194 |
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