Impact of single dose of pegfilgrastim on peripheral blood stem cell harvest in patients with multiple myeloma or malignant lymphoma

Impact of single dose of pegfilgrastim on peripheral blood stem cell harvest in patients with multiple myeloma or malignant lymphoma

Abstract This phase 2 study evaluated the impact of pegfilgrastim, a single-dose, long-acting granulocyte colony-stimulating factor, on the steady-state mobilization of hematopoietic stem cells into peripheral blood in patients with multiple myeloma (MM) or malignant lymphoma (ML). Efficacy and safe...

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Main Authors: Hideki Goto, Masashi Sawa, Shin-ichiro Fujiwara, Masaki Ri, Tadao Ishida, Masahiro Takeuchi, Kenji Ishitsuka, Masako Toyosaki, Kazutaka Sunami, Junichi Tsukada, Takashi Sonoki, Aiko Shimogomi, Yuki Ichihashi, Yoshiumi Ouchi, Toshihiro Miyamoto, Masayuki Hino, Yoshinobu Maeda, Takanori Teshima
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Multiple myeloma
Pegfilgrastim
Lymphoma
CD34
Mobilization
Peripheral blood stem cell
Online Access:https://doi.org/10.1038/s41598-025-98453-7
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https://doi.org/10.1038/s41598-025-98453-7

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