ENPP1 affects insulin action and secretion: evidences from in vitro studies.

ENPP1 affects insulin action and secretion: evidences from in vitro studies.

The aim of this study was to deeper investigate the mechanisms through which ENPP1, a negative modulator of insulin receptor (IR) activation, plays a role on insulin signaling, insulin secretion and eventually glucose metabolism. ENPP1 cDNA (carrying either K121 or Q121 variant) was transfected in H...

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Main Authors: Rosa Di Paola, Nunzia Caporarello, Antonella Marucci, Claudia Dimatteo, Claudia Iadicicco, Silvia Del Guerra, Sabrina Prudente, Dora Sudano, Claudia Miele, Cristina Parrino, Salvatore Piro, Francesco Beguinot, Piero Marchetti, Vincenzo Trischitta, Lucia Frittitta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0019462&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0019462&type=printable

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