Pathobiochemistry of Aging and Neurodegeneration: Deregulation of NAD+ Metabolism in Brain Cells

Pathobiochemistry of Aging and Neurodegeneration: Deregulation of NAD+ Metabolism in Brain Cells

NAD+ plays a pivotal role in energy metabolism and adaptation to external stimuli and stressful conditions. A significant reduction in intracellular NAD+ levels is associated with aging and contributes to the development of chronic cardiovascular, neurodegenerative, and metabolic diseases. It is of...

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Bibliographic Details
Main Authors: Nataliya A. Kolotyeva, Alexander A. Groshkov, Nataliya A. Rozanova, Arseniy K. Berdnikov, Svetlana V. Novikova, Yulia K. Komleva, Alla B. Salmina, Sergey N. Illarioshkin, Mikhail A. Piradov
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomolecules
Subjects:
nicotinamide adenine dinucleotide
NAD+
metabolism
brain
aging
neurodegeneration
Online Access:https://www.mdpi.com/2218-273X/14/12/1556
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