Case Report: The long-term effects of the empagliflozin therapy on glycemia and renal function in a patient with Rabson-Mendenhall syndrome caused by two heterozygous variants in INSR gene

Case Report: The long-term effects of the empagliflozin therapy on glycemia and renal function in a patient with Rabson-Mendenhall syndrome caused by two heterozygous variants in INSR gene

We present a patient with Rabson-Mendenhall syndrome with unsatisfactory glycemic control of diabetes despite the use of metformin, pioglitazone, and sitagliptin. We investigated the long-term effects of treatment with an empagliflozin. After one year of empagliflozin therapy, an improvement in meta...

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Bibliographic Details
Main Authors: Joanna Chrzanowska, Julia Lachowska, Maja Weimann, Agnieszka Zubkiewicz-Kucharska, Konstancja Fornalczyk, Katarzyna Kilis-Pstrusińska, Robert Smigiel
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Endocrinology
Subjects:
Rabson-Mendenhall syndrome
diabetes mellitus
insulin resistance
sodium–glucose cotransporter 2 inhibitors
nephrocalcinosis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1552690/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1552690/full

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