Tazobactam selects for multidrug resistance

Abstract Piperacillin-Tazobactam is a β-lactam/β-lactamase inhibitor combination that is amongst the most prescribed antimicrobials in hospital medicine. Piperacillin is inactivated by many common beta-lactamases, but tazobactam inhibits these, allowing successful treatment. The effect of piperacill...

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Bibliographic Details
Main Authors: Emma R. Holden, Muhammad Yasir, A. Keith Turner, Ian G. Charles, Mark A. Webber
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-025-00122-2
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