Targeting FKBP51 prevents stress-induced preterm birth

Targeting FKBP51 prevents stress-induced preterm birth

Abstract Preterm birth (PTB) is a leading cause of perinatal morbidity and mortality, with maternal stress-related disorders, such as depression and anxiety, linked to idiopathic PTB (iPTB). At the maternal-fetal interface, decidualized stromal cells (DSCs) exclusively express the progesterone recep...

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Bibliographic Details
Main Authors: Ozlem Guzeloglu-Kayisli, Asli Ozmen, Busra Cetinkaya Un, Burak Un, Jacqueline Blas, Isabella Johnson, Andrea Thurman, Mark Walters, David Friend, Umit A Kayisli, Charles J Lockwood
Format: Article
Language:English
Published: Springer Nature 2025-03-01
Series:EMBO Molecular Medicine
Subjects:
15dPGJ2
Maternal Stress
Preterm Birth
FKBP51
Progesterone Receptor
Online Access:https://doi.org/10.1038/s44321-025-00211-9
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https://doi.org/10.1038/s44321-025-00211-9

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