Assessing Diazinon Exposure: A GC-MS/MS Validation Study of BChE Measurement by Point-of-Care Testing and Enzyme Multiplied Immunoassay Technique

Assessing Diazinon Exposure: A GC-MS/MS Validation Study of BChE Measurement by Point-of-Care Testing and Enzyme Multiplied Immunoassay Technique

This study addresses the challenge of accurately assessing diazinon exposure in suspected self-poisoning cases. We evaluated butyrylcholinesterase (BChE) levels using a point-of-care (POCT) whole blood assay (adapted Ellman method) and compared it with the standard plasma Enzyme Multiplied Immunoass...

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Bibliographic Details
Main Authors: Andreea-Camelia Hîrjău, Mihaela Emanuela Crăciun, Ilinca-Mihaela Marandiuc, Gabriel-Lucian Radu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
diazinon
butyrylcholinesterase (BChE)
point-of-care testing (POCT)
EMIT immunoassay
organophosphate poisoning
emergency medicine
Online Access:https://www.mdpi.com/1420-3049/30/11/2382
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