Fucosterol exerts an anti-atherosclerotic action via NF-κB and p38/Erk MAPK signaling pathways

Fucosterol exerts an anti-atherosclerotic action via NF-κB and p38/Erk MAPK signaling pathways

Background: Fucosterol is a sterol isolated from brown algae and has various biological properties, such anti-inflammatory and antidiabetic effects. In this study, we investigated the anti-atherosclerosis effects of fucosterol in vivo and in vitro. Methods: ApoE−/− mice were fed a high fat diet for...

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Main Authors: Tiancheng Liu, Mengli Zhang, Xian Wu, Zhenxing Liu, Huan Peng, Feng Gui, Wen Xiong, Qijuan Liu, Guojun Du, Bo Liu, Chenchen Zhang, Junfeng Ma, Quan Yuan, Wei Li, Zhen Chen
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Atherosclerosis Plus
Subjects:
Atherosclerosis
Fucosterol
Oxidative stress
Inflammation
Endothelial cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2667089525000112
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