A new two-hit animal model for schizophrenia research: Consequences on social behavior

A new two-hit animal model for schizophrenia research: Consequences on social behavior

Schizophrenia, a profoundly impactful neuropsychiatric disorder, has been the subject of extensive research using animal models. However, certain important aspects remain understudied, including assumed long-term consequences of psychotic episodes on negative symptoms development and progression. Ad...

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Bibliographic Details
Main Authors: Kristina Hakenova, Anna Mikulecka, Kristina Holubova, Marketa Chvojkova, Romana Slamberova, Jana Jurcovicova, Barbora Cechova, Silvester Ponist, Jiri Horacek, Karel Vales
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:IBRO Neuroscience Reports
Subjects:
Schizophrenia
Social behavior
negative symptom
Animal model
Two-hit model
Oxytocin
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242125000788
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