Kartogenin‐Loaded Aminated Hollow Mesoporous Prussian Blue Nanozyme‐Reinforced Hydrogel Remodels the Senescent Microenvironment via Reactive Oxygen Species Scavenging and Stimulator of Interferon Genes Inhibition to Promote Cartilage Regeneration

Kartogenin‐Loaded Aminated Hollow Mesoporous Prussian Blue Nanozyme‐Reinforced Hydrogel Remodels the Senescent Microenvironment via Reactive Oxygen Species Scavenging and Stimulator of Interferon Genes Inhibition to Promote Cartilage Regeneration

Articular cartilage defects remain an intractable clinical challenge due to the limited capacity of cartilage for self‐renewal and repair. Excessive accumulation of reactive oxygen species (ROS) leads to mitochondrial dysfunction, inflammation, and chondrocyte senescence, impeding cartilage regenera...

Full description

Saved in:
Bibliographic Details
Main Authors: Shu‐Hang He, Zhi‐Han Shen, Ren Zhang, Po‐Lin Liu, Xu‐Ran Li, Qing‐Song Deng, Yu‐Chen Zhang, Ang Wang, Xiao‐Qiu Dou, Shang‐Chun Guo, Shi‐Cong Tao
Format: Article
Language:English
Published: Wiley-VCH 2025-07-01
Series:Small Structures
Subjects:
cartilage regeneration
nanozyme‐reinforced hydrogel
reactive oxygen species scavenging
senescent microenvironment
stimulator of interferon genes inhibition
Online Access:https://doi.org/10.1002/sstr.202400592
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/sstr.202400592

Similar Items