Alterations in ganglion cell and nerve fiber layer in Leber hereditary optic neuropathy across clinical stages

Abstract Purpose LHON leads to gradual, painless, and permanent vision loss in both eyes, often associated with central scotomas. As the condition progresses, there is a decline in visual function, accompanied by noticeable structural alterations. This study focused on evaluating the clinical charac...

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Bibliographic Details
Main Authors: Michael Oeverhaus, Mareile Knetsch, Ying Chen, Leyla Jabbarli, Carmen Nolden, Anja Eckstein, Nikolaos E. Bechrakis, Philipp Rating
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Ophthalmology
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Online Access:https://doi.org/10.1186/s12886-025-03991-3
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