High-Throughput Method for Isolating Plasmid DNA with Reduced Lipopolysaccharide Content

Isolating plasmid DNA from bacteria is a fundamental step in molecular biology. It is often accomplished by an alkaline lysis of bacteria and the subsequent adsorption of nucleic acids to silica oxide in the presence of chaotropic substances. Here we show that the addition of such chaotropic reagent...

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Bibliographic Details
Main Authors: Frank Neudecker, Stefan Grimm
Format: Article
Language:English
Published: Taylor & Francis Group 2000-01-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/00281st06
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