Exploring Schiff Bases as Promising Alternatives to Traditional Drugs in the In Silico Treatment of Anti-Leishmaniasis as Trypanothione Reductase Inhibitors

Leishmaniasis, caused by the protozoan <i>Leishmania</i> spp. and transmitted by sandflies, affects 2 million people worldwide yearly and is recognized as a global problem by the WHO. Current treatments, including amphotericin B, Pentamidine, and Glucantime, show limited efficacy and ser...

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Bibliographic Details
Main Authors: Diego R. Peixoto, Carlos S. H. Shiraishi, Rui M. V. Abreu, Osmair V. Oliveira, José D. dos Santos
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/102/1/55
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