The association between systemic immune-inflammation index and cardiovascular diseases: An in-depth umbrella review of meta-analyses with GRADE assessment

Background: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. The Systemic Immune-Inflammation Index (SII), an emerging biomarker calculated from platelet, neutrophil, and lymphocyte counts, has gained attention for its potential role in predicting cardiovascular outcomes....

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Bibliographic Details
Main Authors: Kwame Boateng Agyeman, Nimra Shafi, Rafael Contreras, Vishal Parackal, Diyana N. Shah, Anoop Gurram, Narsimha Rao Keetha, Daniyal Ameen
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Heliyon
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Online Access:http://www.sciencedirect.com/science/article/pii/S240584402501117X
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