RAF1 promotes anlotinib resistance in non-small cell lung cancer by inhibiting apoptosis

Abstract Background Anlotinib is an effective treatment for advanced non-small cell lung cancer (NSCLC), but resistance to it often develops during therapy. RAF1, a serine/threonine kinase involved in cancer progression, has limited research in NSCLC, particularly regarding anlotinib resistance. Met...

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Bibliographic Details
Main Authors: Shuo Wu, Chenxi Hu, Pengwu Hu, Wei He, Kaiyuan Hui, Xiaodong Jiang
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Journal of Cancer Research and Clinical Oncology
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Online Access:https://doi.org/10.1007/s00432-025-06175-0
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