Small Extracellular Vesicles with a High Sphingomyelin Content Isolated from Hypertensive Diabetic db/db Mice Inhibits Calcium Mobilization and Augments Amiloride-Sensitive Epithelial Sodium Channel Activity

Extracellular vesicles (EVs) contain bioactive lipids that play a key role in pathophysiology. We hypothesized that EVs released from salt-loaded hypertensive diabetic db/db mice have increased bioactive lipid content that inhibits intracellular calcium mobilization and increases the activity of ren...

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Bibliographic Details
Main Authors: Hunter Ramsay, Ling Yu, Faisal F. Alousi, Abdel A. Alli
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biology
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Online Access:https://www.mdpi.com/2079-7737/14/3/252
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