Proteome Profiling of <i>S. cerevisiae</i> Strains Lacking the Ubiquitin-Conjugating Enzymes Ubc4 and Ubc5 During Exponential Growth and After Heat Shock Treatment

Proteome Profiling of <i>S. cerevisiae</i> Strains Lacking the Ubiquitin-Conjugating Enzymes Ubc4 and Ubc5 During Exponential Growth and After Heat Shock Treatment

The Ubiquitin–Proteasome System (UPS) governs numerous cellular processes by modulating protein stability and activity via the conjugation of the small protein ubiquitin, either as a single molecule or as linkages with distinct functions. Dysregulation of the UPS has been associated with many diseas...

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Bibliographic Details
Main Authors: Valentina Rossio, Xinyue Liu, Joao A. Paulo
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Microorganisms
Subjects:
TMT proteomics
ubiquitin–proteasome system
<i>S. cerevisiae</i>
heat shock
ubiquitin-conjugating enzymes
Online Access:https://www.mdpi.com/2076-2607/12/11/2235
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