GSH-conjugation Reduces PGV-1 Cytotoxicity and Its Ability in Downregulating N-Myc, β-catenin, and p62 Protein in Huh-6 Cells

BACKGROUND: Pentagamuvone-1 (PGV-1), a synthetic curcumin analogue, exhibits potent anticancer activity against Hepatocellular Carcinoma (HCC) by disrupting cell cycle regulation and downregulating key oncogenes such as N-Myc. Numerous studies have examined the role of glutathione (GSH) conjugation...

Full description

Saved in:
Bibliographic Details
Main Authors: Rohmad Yudi Utomo, Edy Meiyanto, Ratna Asmah Susidarti
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2025-08-01
Series:Indonesian Biomedical Journal
Online Access:https://inabj.org/index.php/ibj/article/view/3634
Tags: Add Tag
No Tags, Be the first to tag this record!