Phase synchrony between prefrontal noradrenergic and cholinergic signals indexes inhibitory control

Abstract This study investigates how norepinephrine (NE) and acetylcholine (ACh) in the prefrontal cortex (PFC) modulate inhibitory control, a critical executive function. Using fluorescent sensors, we tracked prefrontal NE/ACh dynamics in mice during inhibitory control tasks and found strong NE-ACh...

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Bibliographic Details
Main Authors: Yuxiang Andy Liu, Yuhan Nong, Jiesi Feng, Guochuan Li, Paul Sajda, Yulong Li, Qi Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62317-5
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