Upregulation of RIG‐I is Critical for Responsiveness to IFN‐α Plus Anti‐PD‐1 in Colorectal Cancer

Upregulation of RIG‐I is Critical for Responsiveness to IFN‐α Plus Anti‐PD‐1 in Colorectal Cancer

ABSTRACT Backgrounds Immunotherapy is a promising and effective approach that has achieved significant curative effects in colorectal cancer (CRC). Recently, retinoic acid‐inducible gene I (RIG‐I) has been shown to play a critical role in tumor immunity. However, the correlation between RIG‐I and im...

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Bibliographic Details
Main Authors: Haihang Nie, Shilin Fang, Rui Zhou, Yifan Jia, Jingkai Zhou, Yumei Ning, Yali Yu, Yuntian Hong, Fei Xu, Qiu Zhao, Jiayan Nie, Fan Wang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Medicine
Subjects:
anti‐PD‐1
bioinformatic analysis
colorectal cancer
combinatorial immunotherapy
interferon‐α
RIG‐I
Online Access:https://doi.org/10.1002/cam4.70802
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https://doi.org/10.1002/cam4.70802

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