IL-18-primed NK cells recruit dendritic cells and potentiate tumor therapy mediated by PD-1 blockade

The success of cancer immunotherapy depends on the effective coordination of innate and adaptive immunity. We previously reported that IL-18 potentiates the therapeutic effects of immune checkpoint inhibitors in mouse models. Here, we report that IL-18-primed natural killer (NK) cells enhanced the a...

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Bibliographic Details
Main Authors: Yoshiya Ohno, Haruki Okamura, Hideo Yagita, Toshiyuki Tanaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1533808/full
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