Comparative study on the possible ameliorative effects of imatinib and ibudilast in a rat model of multiple sclerosis

Comparative study on the possible ameliorative effects of imatinib and ibudilast in a rat model of multiple sclerosis

Abstract Background This is an experimental comparative study of the ameliorative effects of imatinib and ibudilast in multiple sclerosis induced in rats by cuprizone. Forty healthy adult male rats were used and divided into five groups: normal control, solvent control, multiple sclerosis model, ima...

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Bibliographic Details
Main Authors: Monica Gamal Fawzy, Mohsen Sami Selim, Omayma Anwar Khorshid, Laila Ahmed Rashed, Miran Atif Elkordy, Noha Samir Abdel Latif
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Multiple sclerosis
MAPK
MBP
NFκB
Imatinib
Ibudilast
Online Access:https://doi.org/10.1186/s43094-025-00801-x
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https://doi.org/10.1186/s43094-025-00801-x

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