Accurate identification of locally aneuploid cells by incorporating cytogenetic information in single cell data analysis

Abstract Single-cell RNA sequencing is a powerful tool to investigate the cellular makeup of tumor samples. However, due to the sparse data and the complex tumor microenvironment, it can be challenging to identify neoplastic cells that play important roles in tumor growth and disease progression. Th...

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Bibliographic Details
Main Authors: Ziyi Li, Ruoxing Li, Irene Ganan-Gomez, Hussein A. Abbas, Guillermo Garcia-Manero, Wei Sun
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-75226-2
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