Successful Treatment of Innumerable Untreated Brain Metastases With Trastuzumab Deruxtecan in Chemotherapy-Naïve HER2-Mutated Non-Small-Cell Lung Cancer

In non-small-cell lung cancer (NSCLC), activating human epidermal growth factor receptor 2 (HER2) mutations are found in a small subset of patients and are associated with a higher incidence of brain metastases (BMETSs), conferring poor survival outcomes. Trastuzumab deruxtecan (T-DXd) was recently...

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Bibliographic Details
Main Authors: Sara Young, Sean C. Dougherty, Angela M. DeRidder, Camilo E. Fadul, Ryan D. Gentzler
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/crom/9936011
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