Imperatorin Suppresses Aberrant Hedgehog Pathway and Overcomes Smoothened Antagonist Resistance via STAT3 Inhibition

Imperatorin Suppresses Aberrant Hedgehog Pathway and Overcomes Smoothened Antagonist Resistance via STAT3 Inhibition

Juan Wang,1,* Hua Cheng,2,* Xinyue Zhao,1 Xiuwen Zhang,3 Xiaolei Ding,1 Taomin Huang3 1Department of Pharmacy, School of Medicine, Shanghai University, Shanghai, 200444, People’s Republic of China; 2Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massach...

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Bibliographic Details
Main Authors: Wang J, Cheng H, Zhao X, Zhang X, Ding X, Huang T
Format: Article
Language:English
Published: Dove Medical Press 2024-11-01
Series:Drug Design, Development and Therapy
Subjects:
hedgehog
resistance
gli1
imperatorin
stat3
medulloblastoma
Online Access:https://www.dovepress.com/imperatorin-suppresses-aberrant-hedgehog-pathway-and-overcomes-smoothe-peer-reviewed-fulltext-article-DDDT
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