Exosomes from Tregs mitigate lung damage caused by smoking via inhibiting inflammation and altering T lymphocyte subsets in COPD rats

Exosomes from Tregs mitigate lung damage caused by smoking via inhibiting inflammation and altering T lymphocyte subsets in COPD rats

Abstract Background Chronic obstructive pulmonary disease (COPD) is a common disease with respiratory symptoms and limited airflow. Exosomes derived from Tregs (Treg-exo) could regulate immune function and prevent autoimmune disease. This study assessed Treg-exo effects on COPD. Methods In vivo, rat...

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Bibliographic Details
Main Authors: Xuefang Tao, Hai Tian, Guowen Wang, Yongzhen Sun, Liangyan Zhao
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Pulmonary Medicine
Subjects:
T lymphocyte subset
Exosomes
Chronic obstructive pulmonary disease
Lung tissue remodeling
Immune response
Online Access:https://doi.org/10.1186/s12890-025-03632-x
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https://doi.org/10.1186/s12890-025-03632-x

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