A randomized clinical trial of the immunogenicity of 7-valent pneumococcal conjugate vaccine compared to 23-valent polysaccharide vaccine in frail, hospitalized elderly.

A randomized clinical trial of the immunogenicity of 7-valent pneumococcal conjugate vaccine compared to 23-valent polysaccharide vaccine in frail, hospitalized elderly.

<h4>Background</h4>Elderly people do not mount strong immune responses to vaccines. We compared 23-valent capsular polysaccharide (23vPPV) alone versus 7-valent conjugate (PCV7) vaccine followed by 23vPPV 6 months later in hospitalized elderly.<h4>Methods</h4>Participants wer...

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Bibliographic Details
Main Authors: C Raina Macintyre, Iman Ridda, Zhanhai Gao, Aye M Moa, Peter B McIntyre, John S Sullivan, Thomas R Jones, Andrew Hayen, Richard I Lindley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094578&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094578&type=printable

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