Increased antioxidative defense and reduced advanced glycation end-product formation by metabolic adaptation in non-small-cell-lung-cancer patients

Abstract Reactive oxygen species can oxidatively modify enzymes to reroute metabolism according to tumor needs, rendering identification of oxidized proteins important for understanding neoplastic survival mechanisms. Thiol groups are most susceptible to oxidative modifications but challenging to an...

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Bibliographic Details
Main Authors: Tamara Tomin, Sophie Elisabeth Honeder, Laura Liesinger, Daniela Gremel, Bernhard Retzl, Joerg Lindenmann, Luka Brcic, Matthias Schittmayer, Ruth Birner-Gruenberger
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60326-y
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