APP β-CTF triggers cell-autonomous synaptic toxicity independent of Aβ
Aβ is believed to play a significant role in synaptic degeneration observed in Alzheimer’s disease and is primarily investigated as a secreted peptide. However, the contribution of intracellular Aβ or other cleavage products of its precursor protein (APP) to synaptic loss remains uncertain. In this...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2025-04-01
|
| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/100968 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|