Evaluation of the activity of geraniol isolated from lemongrass (<i>Cymbopogon commutatus</i> Stapf.) on ochratoxin A-induced nephrotoxicity: role of the pPI3K/AKT-Nrf2 signaling pathway

Evaluation of the activity of geraniol isolated from lemongrass (<i>Cymbopogon commutatus</i> Stapf.) on ochratoxin A-induced nephrotoxicity: role of the pPI3K/AKT-Nrf2 signaling pathway

Ochratoxin A (OTA) is a mycotoxin that causes immunotoxicity, teratogenicity, hepatotoxicity and nephrotoxicity in humans and animals. Numerous studies have suggested that oxidative stress may increase OTA's nephrotoxicity. Geraniol (GNL), a monoterpene found in many plant oils is an antioxida...

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Main Authors: Rebai Ben Ammar, Shouq Nafea Al Mutairi, Peramaiyan Rajendran, Gamal M. Bekhet, Maged Elsayed Mohamed, Rashid Ismael Hag Ibrahim, Hamad Abu Zahra, Sarah Abdulaziz Alamer, Mohammed Salem Moqbel, Riadh Ksouri
Format: Article
Language:English
Published: PAGEPress Publications 2025-03-01
Series:Journal of Biological Research
Subjects:
Antioxidant properties
geraniol
ochratoxin A
kidney
nephrotoxicity
PI3K/AKT signaling pathway
Online Access:https://www.pagepressjournals.org/jbr/article/view/13166
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