Indirect modeling of derived outcomes: Are minor prediction discrepancies a cause for concern?

Abstract It is often a goal of model development to predict data from which a variety of outcomes can be derived, such as threshold‐based categorization or change from baseline (CFB) transformations. This approach can improve power or support multiple decisions. Because these derivations are indirec...

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Bibliographic Details
Main Author: John P. Prybylski
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13219
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