Systematic evaluation of single-cell RNA-seq analyses performance based on long-read sequencing platforms

Systematic evaluation of single-cell RNA-seq analyses performance based on long-read sequencing platforms

Introduction: The rapid development of next-generation sequencing (NGS)-based single-cell RNA sequencing (scRNA-seq) allows for detecting and quantifying gene expression in a high-throughput manner, providing a powerful tool for comprehensively understanding cellular function in various biological p...

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Bibliographic Details
Main Authors: Enze Deng, Qingmei Shen, Jingna Zhang, Yaowei Fang, Lei Chang, Guanzheng Luo, Xiaoying Fan
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Advanced Research
Subjects:
Single cell RNA-sequencing
Third-generation sequencing
Cell type identification
Novel isoform
Allele-specific gene/isoform
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224002108
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