Involvement of the tryptophan-kynurenine pathway in the pathogenesis of autoimmune diseases

The kynurenine pathway (KP), a major metabolic pathway for L-tryptophan (Trp) in mammals, plays a multifaceted role in various physiological processes, including neural activity, immune system regulation, and the maintenance of intestinal homeostasis. The functional connection between the KP and imm...

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Bibliographic Details
Main Authors: A-Yuan Chen, Ying-Jie Zhao, Yue-Ye Wang, Wei Wei, Wei Hu, Yan Chang
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Experimental Gerontology
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Online Access:http://www.sciencedirect.com/science/article/pii/S0531556525001664
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