Proximity extension assay reveals serum inflammatory biomarkers in two amyotrophic lateral sclerosis cohorts

Proximity extension assay reveals serum inflammatory biomarkers in two amyotrophic lateral sclerosis cohorts

Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease with both clinical and hereditary heterogeneity. Inflammation has been suggested to play an important role in ALS pathophysiology. In this study, we aimed to identify serum inflammatory alterations and develop effective inflamma...

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Main Authors: Yujing Chen, Sujuan Sun, Ninglu Gao, Zetai Bai, Wenfei Yu, Bing Zhao, Yan Yun, Xiaohan Sun, Pengfei Lin, Wei Li, Yuying Zhao, Chuanzhu Yan, Shuangwu Liu
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Neurobiology of Disease
Subjects:
Amyotrophic lateral sclerosis
Biomarker
Inflammation
Proximity extension assay
Mendelian randomization
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996125001494
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