Synergistic Antitumor Effects of Ivermectin and Metformin in Canine Breast Cancer via PI3K/AKT/mTOR Pathway Inhibition

Ivermectin (IVM) is a macrolide antiparasitic drug, and Metformin (MET) is a biguanide oral hypoglycemic drug. Studies have shown that both of them have obvious anti-tumor effects, but there have been no reports on the combined treatment of Canine breast tumors. This report aimed to investigate the...

Full description

Saved in:
Bibliographic Details
Main Authors: Huili Feng, Lixin He, Talha Umar, Xiao Wang, Wenxuan Li, Bohan Zhang, Xinying Zhu, Ganzhen Deng, Changwei Qiu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/47/6/403
Tags: Add Tag
No Tags, Be the first to tag this record!