Dual molecularly imprinted nanocomposite with transferrin mediated glioma targeting and cholesterol exhaustion for synergistic cuproptosis/immune checkpoint blockade/immunogenic cell death

Dual molecularly imprinted nanocomposite with transferrin mediated glioma targeting and cholesterol exhaustion for synergistic cuproptosis/immune checkpoint blockade/immunogenic cell death

Effective therapies for Glioblastoma (GBM) are often challenging by virtue of the intracranial location of GBM tumors, molecular heterogeneity, high recurrence rate, and overall resistance to treatment. Therefore, we proposed the development of doxorubicin (DOX) loaded molecularly imprinted nanocomp...

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Bibliographic Details
Main Authors: Yuting Zhao, Jiayu Yuan, Yao Qi, Mengdi Sun, Yifei Zhang, Ge Zhang, Xiangchen Su, Mingzhu Song, Ruizhen Lv, Yijie Shi, Liang Zhao
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Materials Today Bio
Subjects:
Glioblastoma
Imprinted nanocomposites
Transferrin
Cholesterol
Cuproptosis
Immunogenic cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425007793
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