Long term ingestion of dietary ALEs induces metabolic disorders in mice by inducing gut dysbiosis and inhibiting AMPK/SIRT1 pathway
Advanced lipoxidation end products (ALEs) are formed by modifying proteins with lipid oxidation products. ALEs formed in the body have been linked to diabetes and hepatic disease. However, it is not known whether ALEs formed in heat-processed foods can induce metabolic diseases. Our results indicate...
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| Main Authors: | Yaya Wang, Tianchang Zhang, Linqing Nie, Yan Zhang, Junping Wang, Shuo Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tsinghua University Press
2025-02-01
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| Series: | Food Science and Human Wellness |
| Subjects: | |
| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2024.9250029 |
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