Long term ingestion of dietary ALEs induces metabolic disorders in mice by inducing gut dysbiosis and inhibiting AMPK/SIRT1 pathway

Advanced lipoxidation end products (ALEs) are formed by modifying proteins with lipid oxidation products. ALEs formed in the body have been linked to diabetes and hepatic disease. However, it is not known whether ALEs formed in heat-processed foods can induce metabolic diseases. Our results indicate...

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Bibliographic Details
Main Authors: Yaya Wang, Tianchang Zhang, Linqing Nie, Yan Zhang, Junping Wang, Shuo Wang
Format: Article
Language:English
Published: Tsinghua University Press 2025-02-01
Series:Food Science and Human Wellness
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Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250029
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