Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect.

<h4>Background</h4>Estimates of the sensitivity and specificity for new diagnostic tests based on evaluation against a known gold standard are imprecise when the accuracy of the gold standard is imperfect. Bayesian latent class models (LCMs) can be helpful under these circumstances, but...

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Bibliographic Details
Main Authors: Cherry Lim, Prapass Wannapinij, Lisa White, Nicholas P J Day, Ben S Cooper, Sharon J Peacock, Direk Limmathurotsakul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0079489
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