Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury

Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury

Abstract Brain injury is the leading cause of mortality among patients who survive cardiac arrest (CA). Clinical studies have shown that the presence of post-CA hypoxic hepatitis or pre-CA liver disease is associated with increased mortality and inferior neurological recovery. In our in vivo global...

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Main Authors: Zhiyong Guo, Meixian Yin, Chengjun Sun, Guixing Xu, Tielong Wang, Zehua Jia, Zhiheng Zhang, Caihui Zhu, Donghua Zheng, Linhe Wang, Shanzhou Huang, Di Liu, Yixi Zhang, Rongxing Xie, Ningxin Gao, Liqiang Zhan, Shujiao He, Yifan Zhu, Yuexin Li, Björn Nashan, Schlegel Andrea, Jin Xu, Qiang Zhao, Xiaoshun He
Format: Article
Language:English
Published: Springer Nature 2024-09-01
Series:EMBO Molecular Medicine
Subjects:
Brain Injury
Cardiac Arrest
Normothermic Machine Perfusion
Liver Dysfunction
Ketone Body Production
Online Access:https://doi.org/10.1038/s44321-024-00140-z
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https://doi.org/10.1038/s44321-024-00140-z

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