Human Pharmacokinetics and Adverse Effects of Pulmonary and Intravenous THC-CBD Formulations

Background: Due to variable absorption and extensive first-pass metabolism, the bioavailability of oral delta-9-tetra­hydrocannabinol (THC) and cannabidiol (CBD) is low, and, therefore, alternative application forms are necessary. Methods: In an open-label, 2-period phase-1 study on 11 he...

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Bibliographic Details
Main Authors: Pascale Meyer, Manuela Langos, Rudolf Brenneisen
Format: Article
Language:English
Published: Karger Publishers 2018-06-01
Series:Medical Cannabis and Cannabinoids
Online Access:https://karger.com/article/doi/10.1159/000489034
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