TFIIB-related factor 2 inhibits lung squamous carcinoma cell apoptosis through SLC8A3-mediated mitochondrial homeostasis
Abstract Lung cancer is the most common cancer and the leading cause of cancer-related deaths. Developing therapies for lung cancer is challenging, and new targets are urgently required. TFIIB-related factor 2 (BRF2) plays a crucial role in the development and progression of various tumors. However,...
Saved in:
| Main Authors: | Shen Yi, Xing Qi, Fei Luo, Dingxin Wang, Zitong Feng, Luyuan Ma, Wenhao Yu, Cong Wang, Hui Tian, Ming Lu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07813-8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Rapidly Inhibiting the Inflammatory Cytokine Storms and Restoring Cellular Homeostasis to Alleviate Sepsis by Blocking Pyroptosis and Mitochondrial Apoptosis Pathways
by: Jiahui Yan, et al.
Published: (2023-05-01) -
Therapeutic Potential of Umbelliferone in Maintaining Epidermal Barrier Integrity by Regulating Mitochondrial Homeostasis and Inhibiting Apoptosis in Diabetic Skins
by: Dong Yeon Kim, et al.
Published: (2025-05-01) -
SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome
by: Alexandre Janer, et al.
Published: (2016-07-01) -
Creatine transporter (SLC6A8) knockout mice exhibit reduced muscle performance, disrupted mitochondrial Ca2+ homeostasis, and severe muscle atrophy
by: Irene Pertici, et al.
Published: (2025-02-01) -
Mitochondrial SLC25A10 promotes prostate cancer progression by inhibiting ferritinophagy
by: Guopeng Yu, et al.
Published: (2025-05-01)