TFIIB-related factor 2 inhibits lung squamous carcinoma cell apoptosis through SLC8A3-mediated mitochondrial homeostasis

Abstract Lung cancer is the most common cancer and the leading cause of cancer-related deaths. Developing therapies for lung cancer is challenging, and new targets are urgently required. TFIIB-related factor 2 (BRF2) plays a crucial role in the development and progression of various tumors. However,...

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Bibliographic Details
Main Authors: Shen Yi, Xing Qi, Fei Luo, Dingxin Wang, Zitong Feng, Luyuan Ma, Wenhao Yu, Cong Wang, Hui Tian, Ming Lu
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07813-8
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