Ready, Set…Poised!: Polycomb target genes are bound by poised RNA polymerase II throughout differentiation
Abstract In embryonic stem cells (ESCs), silent genes with major developmental functions display a unique epigenetic state in which strong and broad binding by Polycomb repressive complexes (PRCs) is accompanied by the presence of poised RNA polymerase II (RNAPII) and activating histone marks (e.g....
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2017-10-01
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| Series: | Molecular Systems Biology |
| Online Access: | https://doi.org/10.15252/msb.20177968 |
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