Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review

Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an i...

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Main Authors: Alaa Eldin Elsharkawy, Raid Abuamona, Markus Bergmann, Shadi Salem, Evariste Gafumbegete, Ernst Röttger
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2013/354873
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author Alaa Eldin Elsharkawy
Raid Abuamona
Markus Bergmann
Shadi Salem
Evariste Gafumbegete
Ernst Röttger
author_facet Alaa Eldin Elsharkawy
Raid Abuamona
Markus Bergmann
Shadi Salem
Evariste Gafumbegete
Ernst Röttger
author_sort Alaa Eldin Elsharkawy
collection DOAJ
description Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an intra- and extra-axial lesion. Intraoperatively, the lesion was a cortical solid mass that had no connections to the dura or to the ventricle. The histological diagnosis showed an anaplastic ependymoma with WHO grade III with distinctive desmoplasia. A literature review of ectopic anaplastic ependymomas regarding their clinical presentations, management, and prognostic factors was performed. There is a need to establish a clinically based histopathological grading system for anaplastic ependymomas. Ectopic anaplastic ependymomas should be included in the preoperative differential diagnosis.
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language English
publishDate 2013-01-01
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series Case Reports in Oncological Medicine
spelling doaj-art-b885beb29b684295a38bfc0b2c5557ad2025-02-03T01:21:39ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/354873354873Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature ReviewAlaa Eldin Elsharkawy0Raid Abuamona1Markus Bergmann2Shadi Salem3Evariste Gafumbegete4Ernst Röttger5Neurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, GermanyNeurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, GermanyDepartment of Clinical Neuropathology, Bremen, GermanyNeurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, GermanyPathological Department, Ludmillenstift Hospital, Meppen, GermanyNeurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, GermanyEctopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an intra- and extra-axial lesion. Intraoperatively, the lesion was a cortical solid mass that had no connections to the dura or to the ventricle. The histological diagnosis showed an anaplastic ependymoma with WHO grade III with distinctive desmoplasia. A literature review of ectopic anaplastic ependymomas regarding their clinical presentations, management, and prognostic factors was performed. There is a need to establish a clinically based histopathological grading system for anaplastic ependymomas. Ectopic anaplastic ependymomas should be included in the preoperative differential diagnosis.http://dx.doi.org/10.1155/2013/354873
spellingShingle Alaa Eldin Elsharkawy
Raid Abuamona
Markus Bergmann
Shadi Salem
Evariste Gafumbegete
Ernst Röttger
Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review
Case Reports in Oncological Medicine
title Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review
title_full Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review
title_fullStr Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review
title_full_unstemmed Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review
title_short Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review
title_sort cortical anaplastic ependymoma with significant desmoplasia a case report and literature review
url http://dx.doi.org/10.1155/2013/354873
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